Golovko lab recognized by American Society for Biochemistry and Molecular Biology

The American Society for Biochemistry and Molecular Biology (ASBMB), publisher of the Journal of Lipid Research, has highlighted a paper published in the journal by Associate Professor Mikhail Golovko’s Department of Biomedical Sciences laboratory.

As an ASBMB story puts it, referencing the paper’s UND-based lead author, “Derek Besch from the University of North Dakota and colleagues…quantified prostanoid (PG) and arachidonic acid levels in murine brain tissue samples without fixation and samples fixed via microwave irradiation (MW) or saline water boiling by ultra-high-pressure liquid chromatography–mass spectrometry. Their results showed that boiling the brain samples in saline water neither alters the morphology nor PG levels compared to other fixation methods.”

This is important, says the ASBMB, because the paper (entitled “A simplified method for preventing postmortem alterations of brain prostanoids for true in situ level quantification”) defines a new, inexpensive method that “could allow for more detailed brain tissue study of other labile metabolites and help in understanding complex neurological processes that may be responsible for different diseases.”

Learn more about Dr. Golovko’s mass spectrometry research at the mass spec website.