{"id":4802,"date":"2020-01-23T13:47:39","date_gmt":"2020-01-23T19:47:39","guid":{"rendered":"https:\/\/blogs.und.edu\/for-your-health\/?p=4802"},"modified":"2020-01-31T08:30:45","modified_gmt":"2020-01-31T14:30:45","slug":"sens-burd-henry-report-significant-research-findings","status":"publish","type":"post","link":"https:\/\/blogs.und.edu\/for-your-health\/2020\/01\/23\/sens-burd-henry-report-significant-research-findings\/","title":{"rendered":"Burd, Sens, Henry report significant research findings"},"content":{"rendered":"<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-4850 size-full\" src=\"https:\/\/blogs.und.edu\/for-your-health\/\/wp-content\/uploads\/sites\/10\/2020\/01\/burd-henry-sens.jpg\" alt=\"\" width=\"800\" height=\"475\" srcset=\"https:\/\/blogs.und.edu\/for-your-health\/wp-content\/uploads\/sites\/10\/2020\/01\/burd-henry-sens.jpg 800w, https:\/\/blogs.und.edu\/for-your-health\/wp-content\/uploads\/sites\/10\/2020\/01\/burd-henry-sens-300x178.jpg 300w, https:\/\/blogs.und.edu\/for-your-health\/wp-content\/uploads\/sites\/10\/2020\/01\/burd-henry-sens-768x456.jpg 768w, https:\/\/blogs.und.edu\/for-your-health\/wp-content\/uploads\/sites\/10\/2020\/01\/burd-henry-sens-600x356.jpg 600w, https:\/\/blogs.und.edu\/for-your-health\/wp-content\/uploads\/sites\/10\/2020\/01\/burd-henry-sens-200x118.jpg 200w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/>Three SMHS researchers this week reported publishing significant research findings in a pair of peer-reviewed journals.<\/p>\n<p>A lifelong fetal alcohol spectrum disorders (FASD) and SIDS researcher, Department of Pediatrics Professor Larry Burd, Ph.D., reported the end of an embargo on a paper he, SMHS Department of Pathology Chair Mary Ann Sens, M.D., Ph.D., and others published in <em>The Lancet<\/em>&#8216;s\u00a0<em><a href=\"https:\/\/www.thelancet.com\/journals\/eclinm\/home\">EClinicalMedicine<\/a><\/em>\u00a0describing the almost 12-fold increase in SIDS incidence among children exposed to alcohol and cigarette smoke after the first trimester, relative to unexposed fetuses.<\/p>\n<p>\u201cThis is the first multinational, longitudinal study showing that infants exposed to alcohol and cigarettes beyond the first trimester have considerably higher risk for SIDS,\u201d said Burd, who worked on the alcohol exposure portions of the report. \u201cWe enrolled almost 11,900 women in North and South Dakota and South Africa, and followed babies up to one year of age looking at development problems, birth defects, stillbirth rates.\u201d<\/p>\n<p>Burd, said that while a correlation between SIDS and smoking was established years ago, the literature on SIDS and alcohol has been mixed. But this new paper puts any ambiguity to rest.<\/p>\n<p>\u201cWhat we found is that exposure to alcohol and smoke combined had what we call a \u2018synergistic effect\u2019 on SIDS risk that was substantially higher than exposure to just alcohol or cigarettes individually,\u201d Burd added. \u201cThis increased risk was unique to SIDS and did not correlate to other non-SIDS infant deaths.\u201d<\/p>\n<p>Read Dr. Burd&#8217;s and Dr. Sens&#8217;s paper <a href=\"https:\/\/www.thelancet.com\/journals\/eclinm\/article\/PIIS2589-5370(19)30256-1\/fulltext\">online here<\/a>.<\/p>\n<p>Likewise, Associate Professor in the SMHS Department of Biomedical Sciences, Keith Henry, Ph.D., reported the publication of research findings he contributed to that appear to reverse cardiomyopathy and halt vision loss in humans that harbor a certain genetic mutation.<\/p>\n<p>The study provided supplements of the amino acid taurine to a consanguineous cohort of subjects in Pakistan suffering from a defect in the SLC6A6 gene, which encodes a transporter protein that carries taurine, an amino acid essential for the functioning of the retina, heart, and other systems such as connective tissue. The defect results in taurine deficiency, which leads gradually to loss of retinal integrity and impaired heart function.<\/p>\n<p>But Dr. Henry&#8217;s group found that taurine supplementation could overcome the defective transporter and as a result halt vision loss and reverse the cardiomyopathy.<\/p>\n<p>Read the <a href=\"https:\/\/www.eurekalert.org\/pub_releases\/2020-01\/udg-cav012120.php\">full news release on the study here<\/a>.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Three SMHS researchers this week reported publishing significant research findings in a pair of peer-reviewed journals. A lifelong fetal alcohol spectrum disorders (FASD) and SIDS researcher, Department of Pediatrics Professor Larry Burd, Ph.D., reported the end of an embargo on a paper he, SMHS Department of Pathology Chair Mary Ann Sens, M.D., Ph.D., and others [&hellip;]<\/p>\n","protected":false},"author":36,"featured_media":4850,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[7],"tags":[422,423,826,420,421,825,647,828,827],"class_list":["post-4802","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news","tag-alcohol","tag-burd","tag-cardiomyopathy","tag-fas","tag-fetal","tag-henry","tag-sens","tag-sids","tag-taurine"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.6 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Burd, Sens, Henry report significant research findings - For Your Health<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/blogs.und.edu\/for-your-health\/2020\/01\/23\/sens-burd-henry-report-significant-research-findings\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Burd, Sens, Henry report significant research findings - For Your Health\" \/>\n<meta property=\"og:description\" content=\"Three SMHS researchers this week reported publishing significant research findings in a pair of peer-reviewed journals. A lifelong fetal alcohol spectrum disorders (FASD) and SIDS researcher, Department of Pediatrics Professor Larry Burd, Ph.D., reported the end of an embargo on a paper he, SMHS Department of Pathology Chair Mary Ann Sens, M.D., Ph.D., and others [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/blogs.und.edu\/for-your-health\/2020\/01\/23\/sens-burd-henry-report-significant-research-findings\/\" \/>\n<meta property=\"og:site_name\" content=\"For Your Health\" \/>\n<meta property=\"article:published_time\" content=\"2020-01-23T19:47:39+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2020-01-31T14:30:45+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/blogs.und.edu\/for-your-health\/\/srv\/htdocs\/wp-content\/uploads\/sites\/10\/2020\/01\/burd-henry-sens.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"800\" \/>\n\t<meta property=\"og:image:height\" content=\"475\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Brian Schill\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Brian Schill\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"2 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/blogs.und.edu\\\/for-your-health\\\/2020\\\/01\\\/23\\\/sens-burd-henry-report-significant-research-findings\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/blogs.und.edu\\\/for-your-health\\\/2020\\\/01\\\/23\\\/sens-burd-henry-report-significant-research-findings\\\/\"},\"author\":{\"name\":\"Brian Schill\",\"@id\":\"https:\\\/\\\/blogs.und.edu\\\/for-your-health\\\/#\\\/schema\\\/person\\\/c902be5161f180ccfbae046119a5d3b7\"},\"headline\":\"Burd, Sens, Henry report significant research findings\",\"datePublished\":\"2020-01-23T19:47:39+00:00\",\"dateModified\":\"2020-01-31T14:30:45+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/blogs.und.edu\\\/for-your-health\\\/2020\\\/01\\\/23\\\/sens-burd-henry-report-significant-research-findings\\\/\"},\"wordCount\":399,\"image\":{\"@id\":\"https:\\\/\\\/blogs.und.edu\\\/for-your-health\\\/2020\\\/01\\\/23\\\/sens-burd-henry-report-significant-research-findings\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/blogs.und.edu\\\/for-your-health\\\/wp-content\\\/uploads\\\/sites\\\/10\\\/2020\\\/01\\\/burd-henry-sens.jpg\",\"keywords\":[\"alcohol\",\"burd\",\"cardiomyopathy\",\"fas\",\"fetal\",\"henry\",\"sens\",\"sids\",\"taurine\"],\"articleSection\":[\"News\"],\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/blogs.und.edu\\\/for-your-health\\\/2020\\\/01\\\/23\\\/sens-burd-henry-report-significant-research-findings\\\/\",\"url\":\"https:\\\/\\\/blogs.und.edu\\\/for-your-health\\\/2020\\\/01\\\/23\\\/sens-burd-henry-report-significant-research-findings\\\/\",\"name\":\"Burd, Sens, Henry report significant research findings - 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